Two sample MR report
SMDT1_Monocyte (Mono) against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 13 | 0.0065489 | 0.0638806 | 0.9201908 |
| Weighted median | 13 | 0.0264118 | 0.0121236 | 0.0293651 |
| Inverse variance weighted | 13 | 0.0204781 | 0.0096842 | 0.0344647 |
| Simple mode | 13 | 0.0309450 | 0.0197288 | 0.1427384 |
| Weighted mode | 13 | 0.0330249 | 0.0178690 | 0.0893608 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.140493 | 11 | 0.9887358 |
| Inverse variance weighted | 3.189157 | 12 | 0.9940548 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.008089 | 0.0366683 | 0.8294448 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0007995 | 0 | TRUE | 0.0071322 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
